个人简介

何星儒，DrPH MBA MPH，何氏集团数字医疗首席科学家，辽宁何氏医学院公共卫生学院院长，副教授。国际防盲协会(IAPB)眼科英雄未来领袖，美国约翰斯·霍普金斯大学布隆伯格公共卫生学院 Delta Omega(Alpha Chapter)公共卫生荣誉协会终身成员，美国约翰斯·霍普金斯大学布隆伯格公共卫生学院世纪学者代表，中国医疗器械行业协会数字疗法专委会常务委员，沈阳市高层次人才拔尖人才

学习经历

2008.9-2012.6美国 加州大学戴维斯分校 生物科技与科技管理专业 科学学士

2013.6英国伦敦大学卫生与热带医学学院培训课程“为达到视觉 2020 的眼健康体系”

2014.6-2016.3美国 约翰斯·霍普金斯大学布隆伯格公共卫生学院公共卫生硕士(公共卫生经济专修)

2014.6-2016.3美国 约翰斯·霍普金斯大学 凯瑞商学院 工商管理硕士

2016.9-2020.5美国 约翰斯·霍普金斯大学 布隆伯格公共卫生学院卫生政策与管理部 公共卫生博士

工作经历

2012.9-2013.3美国Seros Medical, LLC. 生物医学工程顾问

2013.3-2014.5辽宁何氏眼科医院集团股份有限公司企划部职员

2014.6-2020.5辽宁何氏眼科医院集团股份有限公司防盲治盲部国际防盲研究员

2015.6-2015.8世界卫生组织防盲与防聋部特别研究员

2020.6-至今辽宁何氏医学院公共卫生学院院长副教授

研究方向

眼科卫生政策与管理中的公共卫生评估、干预制定、以及防盲管理，视觉智能(AI, Visual Data Analytics, Meta) 新技术在眼科公共卫生项目和研究中的落地应用。

主要学术任职

中国医疗器械行业协会数字疗法专委会常务委员

主持课题情况(近5年)

1.辽宁何氏医学院，基于视网膜眼底照片对冠心病预判的筛查模型-多维数据机器学习模型搭建与评估，2021.9-2023.8，3.6万。

2.辽宁省教育厅，智能筛查设备的卫生经济评估分析，2021.11-2023.08，20万。

3.辽宁省科学技术厅，运用机器学习的方法搭建并评估眼脑预测模型，2022.09-2024.08，3万。

4.辽宁何氏医学院，眼科知识图谱构建与应用，2023.3-2024.3，20万。

代表性论文（近5年）（*通讯作者）

Qin G, Chen J, Hu L, Qi Y, Xu L, He W, Yu S, Pazo EE,*He X. Protocol for a parallel assignment prospective, randomised, double-blinded, placebo-controlled trial to evaluate the efficacy of 0.01% atropine for near work-induced transient myopia and myopic progression in China. BMJ Open. 2023 Dec 20;13(12):e079833. doi: 10.1136/bmjopen-2023-079833. PMID: 38128934; PMCID: PMC10748874.

Qin G, Chen J, Li L, Qi Y, Chen Y, Zhang Q, Wu Y, You Y, Yang L, Guo N, Moutari S, Bu S, Moore JE, Xu L, He W, Yu S,*He X, Pazo EE. Effects of Diquafosol Sodium Ophthalmic Solution on Tear Film Matrix Metallopeptidase-9 and Corneal Nerve Density in Patients with Type 2 Diabetic Dry Eye. J Ocul Pharmacol Ther. 2023 Dec 13. doi: 10.1089/jop.2023.0098. Epub ahead of print. PMID: 38100078.

Chen J, Chen Y, Qin G, Li L, Li M, Cheng Y, Zhuang S, Li Z, Zhang Q, Wu Y, Yang L, Moutari S, Moore JE, Xu L, He W, Yu S, Pazo EE,*He X. A protocol for a single center, randomized, controlled trial comparing the clinical efficacy of 3% diquafosol and 0.1% hyaluronic acid in diabetic patients with dry eye disease. Trials. 2023 Dec 12;24(1):803. doi: 10.1186/s13063-023-07818-8. PMID: 38087329; PMCID: PMC10714480.

Chen J, Qin G, Li L, Qi Y, Xia Y, Zhang Q, Wu Y, You Y, Yang L, Guo N, Moutari S, Moore JE, Bu S, Xu L, He W, Yu S, Pazo EE,*He X. Correction: The Combined Impact of Intense Pulsed Light Combined and 3% Diquafosol Ophthalmic Solution on Evaporative Dry Eye: A Randomized Control Study. Ophthalmol Ther. 2023 Dec;12(6):2973-2975. doi: 10.1007/s40123-023-00806-w. Erratum for: Ophthalmol Ther. 2023 Dec;12(6):2959-2971. PMID: 37713066; PMCID: PMC10640546.

Chen J, Qin G, Li L, Qi Y, Xia Y, Zhang Q, Wu Y, You Y, Yang L, Guo N, Moutari S, Moore JE, Bu S, Xu L, He W, Yu S, Pazo EE,*He X. The Combined Impact of Intense Pulsed Light Combined and 3% Diquafosol Ophthalmic Solution on Evaporative Dry Eye: A Randomized Control Study. Ophthalmol Ther. 2023 Dec;12(6):2959-2971. doi: 10.1007/s40123-023-00784-z. Epub 2023 Aug 17. Erratum in: Ophthalmol Ther. 2023 Sep 15;: PMID: 37589932; PMCID: PMC10640412.

Qin G, Luan X, Chen J, Li L, He W, Eric Pazo E,He X, Yu S. Effects of insomnia on symptomatic dry eye during COVID-19 in China: An online survey. Medicine (Baltimore). 2023 Nov 17;102(46):e35877. doi:10.1097/MD.0000000000035877. PMID: 37986399; PMCID: PMC10659669.

Zhang Q, Wu Y, Huang H, Qin G, Li L, Chen J, Che H, Xu L, Moore JE, He W, Yu S, Pazo EE,He X. The influence of pupil diameter upon and subjective quality of vision following implantable collamer lens (ICL V4c) implantation: An observational study. Medicine (Baltimore). 2023 Oct 6;102(40):e35198. doi: 10.1097/MD.0000000000035198. PMID: 37800803; PMCID: PMC10553097.

Qin G, Chen J, Li L, Qi Y, Zhang Q, Wu Y, You Y, Yang L, Moore J, Xu L, He W, Yu S, Pazo EE,*He X. Relationship between ocular surface pain and corneal nerve loss in dry eye diabetics: a cross-sectional study in Shenyang, China. BMJ Open. 2023 Sep 26;13(9):e076932. doi: 10.1136/bmjopen-2023-076932. PMID: 37751961; PMCID: PMC10533686.

Chen J, Qin G, Li L, Qi Y, Che H, Huang H, Xia Y, Zhang Q, Wu Y, Yang L, Moutari S, Moore JE, Xu L, He W, Yu S, Pazo EE,*He X. Protocol for a parallel assignment prospective, randomised, comparative trial to evaluate the safety and efficacy of intense pulsed light (IPL) combined with 3% diquafosol (DQS) ophthalmic solution in dry eye syndrome. BMJ Open. 2023 Aug 29;13(8):e073055. doi: 10.1136/bmjopen-2023-073055. PMID: 37643847; PMCID: PMC10465902.

Li L, Chen J, Qin G, Qi Y, Chen Y, Li M, Zhang Q, Cheng Y, Guo N, Moutari S, Moore JE, Yu S,*He X, Pazo EE. Tear Film Lipid Layer Changes Following Combined Effect of Heated Eye Mask with Intense Pulsed Light Therapy for Evaporative Dry Eye: A Randomized Control Study. Photobiomodul Photomed Laser Surg. 2023 Aug;41(8):435-444. doi: 10.1089/photob.2023.0051. PMID: 37579133; PMCID: PMC10460692.

Qin G, Chen J, Li L, Zhang Q, Xu L, Yu S, He W,He X, Pazo EE. Efficacy of intense pulsed light therapy on signs and symptoms of dry eye disease: A meta-analysis and systematic review. Indian J Ophthalmol. 2023 Apr;71(4):1316-1325. doi: 10.4103/IJO.IJO_2987_22. PMID: 37026263; PMCID: PMC10276661.

Qin G, Chen J, Li L, Xia Y, Zhang Q, Wu Y, Yang L, Moutari S, Moore JE, Xu L, He W, Yu S,*He X, Pazo EE. Managing Severe Evaporative Dry Eye with Intense Pulsed Light Therapy. Ophthalmol Ther. 2023 Apr;12(2):1059-1071. doi: 10.1007/s40123-023-00649-5. Epub 2023 Jan 24. PMID: 36693992; PMCID: PMC10011255.

Liu L, Wu X, Lin D, Zhao L, Li M, Yun D, Lin Z, Pang J, Li L, Wu Y, Lai W, Xiao W, Shang Y, Feng W, Tan X, Li Q, Liu S, Lin X, Sun J, Zhao Y, Yang X, Ye Q, Zhong Y, Huang X, He Y, Fu Z, Xiang Y, Zhang L, Zhao M, Qu J, Xu F, Lu P, Li J, Xu F, Wei W, Dong L, Dai G,He X, Yan W, Zhu Q, Lu L, Zhang J, Zhou W, Meng X, Li S, Shen M, Jiang Q, Chen N, Zhou X, Li M, Wang Y, Zou H, Zhong H, Yang W, Shou W, Zhong X, Yang Z, Ding L, Hu Y, Tan G, He W, Zhao X, Chen Y, Liu Y, Lin H. DeepFundus: A flow-cytometry-like image quality classifier for boosting the whole life cycle of medical artificial intelligence. Cell Rep Med. 2023 Feb 21;4(2):100912. doi: 10.1016/j.xcrm.2022.100912. Epub 2023 Jan 19. PMID: 36669488; PMCID: PMC9975093.

Song Y, Yu S,He X, Yang L, Wu Y, Qin G, Zhang Q, Deep Singh Talwar G, Xu L, Moore JE, He W, Pazo EE. Tear film interferometry assessment after intense pulsed light in dry eye disease: A randomized, single masked, sham-controlled study. Cont Lens Anterior Eye. 2022 Aug;45(4):101499. doi: 10.1016/j.clae.2021.101499. Epub 2021 Aug 22. PMID: 34433517.

Zhang Q, Zhang H, Qin G, Wu Y, Song Y, Yang L, Yu S,He X, Moore JE, Moutari S, Palme C, Xu L, He W, Pazo EE. Impact of Diquafosol Ophthalmic Solution on Tear Film and Dry Eye Symptom in Type 2 Diabetic Dry Eye: A Pilot Study. J Ocul Pharmacol Ther. 2022 Mar;38(2):133-140. doi: 10.1089/jop.2021.0083. Epub 2022Jan 19. PMID: 35049373.

研究生培养情况

硕士研究生指导：2019年开始，共指导5人，已毕业4人。

博士研究生指导：2021年开始，共指导2人，已毕业0人。

联系方式

邮箱：hexingru@huh.edu.cn.